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无症状颈动脉狭窄的脑结构和功能MRI研究进展

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无症状颈动脉狭窄(asymptomatic carotid stenosis,ACS)指从未或既往3~6个月内无中度颅外段颈内动脉狭窄(狭窄率≥50%)引起神经系统症状的疾病,是血管性认知功能障碍病因之一,可进展为血管性痴呆.但ACS在MRI中无特异性影像学表现,与其多领域认知受损并不相符,引起国内外研究人员关注.通过近年来相关文献总结发现,既往研究着重于基于结构或静息态功能研究,缺乏结构和功能耦合对ACS脑结构和功能异常全面分析,因此,本文从结构和功能MRI角度对ACS研究进展进行综述,以期为ACS认知受损机制提供了一些新的见解.
Advances in structural and functional imaging in asymptomatic carotid artery stenosis
Asymptomatic carotid stenosis(ACS)refers to a condition where there have been no neurological symptoms caused by moderate extracranial internal carotid artery stenosis(stenosis rate ≥ 50%)within the past 3 to 6 months or ever before.ACS is one of the causes of vascular cognitive impairment and may progress to vascular dementia.However,ACS lacks specific imaging features on MRI,which does not correspond to its multifield cognitive impairment,drawing attention from researchers worldwide.A review of recent literature reveals that previous studies have mainly focused on structural or resting-state functional research,lacking a comprehensive analysis of structural and functional coupling in ACS-related brain structure and function abnormalities.Therefore,this article reviews research progress on ACS from the perspective of structural and functional MRI,aiming to provide new insights into the mechanisms underlying cognitive impairment in ACS.

asymptomatic carotid stenosisimpaired cognitive functionmagnetic resonance imagingbrain structurebrain functionbrain network

王俊君、宋林峰、田彬琳、江林

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遵义医科大学第三附属医院(遵义市第一人民医院)影像科,遵义 563000

无症状颈动脉狭窄 认知功能受损 磁共振成像 脑结构 脑功能 脑网络

2024

磁共振成像
中国医院协会 首都医科大学附属北京天坛医院

磁共振成像

CSTPCD北大核心
影响因子:1.38
ISSN:1674-8034
年,卷(期):2024.15(11)