Chinese expert consensus on the evaluation of abdominal immune-related adverse reactions in malignant tumors treated with immune checkpoint inhibitors by MRI
Chinese expert consensus on the evaluation of abdominal immune-related adverse reactions in malignant tumors treated with immune checkpoint inhibitors by MRI
The advent of Immune checkpoint inhibitors(ICIs)has heralded a new era in the immunotherapy of malignant tumors.Despite this,the accompanying immune-related adverse events(irAEs)have become a major challenge in the treatment process.Among them,the abdomen is the most common site for irAEs to occur,and abdominal irAEs are also the most common reason for the discontinuation of immunotherapy.MRI plays a key role in detecting and evaluating abdominal irAEs.Therefore,early diagnosis and assessment of abdominal irAEs through MRI is crucial.However,there is currently a lack of standardized consensus on MRI examination and diagnosis of abdominal irAEs caused by ICIs in China.To this end,the Molecular Imaging Group,Abdominal Group,and Magnetic Resonance Group of the Radiology Branch of the Chinese Medical Association,as well as the Editorial Board of Chinese Journal of Magnetic Resonance Imaging are committed to formulating a consensus on MRI scanning protocols and diagnostic reporting for abdominal irAEs caused by ICIs.This committee has reached this consensus based on literature,expert experience,and internal discussions among committee members.The consensus aims to standardize the application of MRI in tumor immunotherapy,optimize the assessment of abdominal irAEs,and provide a solid imaging basis for clinical practice.
关键词
磁共振成像/免疫检查点抑制剂/腹部免疫相关不良反应/临床应用/专家共识
Key words
magnetic resonance imaging/immune checkpoint inhibitors/abdominal immune-related adverse events/clinical application/expert consensus