目的 以超高分辨率CT(ultra-high-resolution CT,U-HRCT)为标准,探讨7.0 T磁共振磁敏感加权成像(susceptibility weighted imaging,SWI)序列在膝关节骨微结构成像中的评估能力.材料与方法 前瞻性招募陆军军医大学第一附属医院2022年12月至2023年3月行膝关节U-HRCT扫描的31例患者,一周内行7.0 T磁共振膝关节扫描.所有数据经西门子Syngovia处理,分别测量膝关节U-HRCT和7.0 T SWI序列髌骨上下缘相同解剖层面的股骨后份骨皮质厚度,使用Bone J软件对膝关节U-HRCT和7.0 T SWI髌骨上下缘及胫骨平台相同解剖层面行骨小梁拟合度分析,以U-HRCT为标准评估SWI对骨质微结构显示能力.结果 在髌骨上缘层面股骨后份皮质厚度,MRI测值高于CT测值[(0.320±0.020)mm vs.(0.230±0.025)mm,t=19,P<0.001];髌骨下缘层面股骨后份骨皮质厚度,MRI测值高于CT测值[(0.260±0.021)mm vs.(0.158±0.028)mm,t=21,P<0.001].髌骨上缘层面,股骨骨小梁CT和MRI拟合度为47%±11%,髌骨下缘层面,股骨骨小梁CT和MRI拟合度为53%±10%,胫骨平台骺线上水平缘层面胫骨骨小梁CT和MRI拟合度为55%±6%.结论 在7.0 T磁共振下,SWI能够较准确显示膝关节股骨后份骨皮质厚度,但在骨小梁结构的显示方面存在一定局限性.
Evaluation of the display ability of 7.0 T magnetic resonance SWI sequence for knee bone microstructure using U-HRCT as a standard
Objective:To investigate the ability of 7.0 T magnetic resonance magnetic susceptibility weighted imaging(SWI)sequences to assess bone microarchitecture imaging of the knee joint using ultra-high-resolution CT(U-HRCT)as a standard.Materials and Methods:Analysis of 31 patients who underwent U-HRCT scanning of the knee from December 2022 to March 2023 at the First Affiliated Hospital of the Army Medical University,who underwent 7.0 T MRI knee scanning within one week.All data were processed by Siemens Syngovia,and the cortical thickness of the posterior portion of the femur was measured at the same anatomical level of the upper and lower margins of the patella in the knee U-HRCT and 7.0 T SWI sequences,respectively,and trabecular fit analyses were performed at the same anatomical level of the upper and lower margins of the patella and the tibial plateau in the knee U-HRCT and 7.0 T SWI,using the Bone J software,to assess the UHRCT as the standard SWI's ability to display bone microstructure.Results:Cortical thickness of the posterior femur at the level of the superior patellar margin was significantly higher in MRI than in CT[(0.320±0.020)mm vs.(0.230±0.025)mm,t=19,P<0.001],and cortical thickness of the posterior femur at the level of the inferior patellar margin was significantly higher in MRI than in CT[(0.260±0.021)mm vs.(0.158±0.028)mm,t=21,P<0.001].At the level of the superior patellar rim,the CT and MRI fit of the femoral trabeculae was 47%±11%,at the level of the inferior patellar rim,the CT and MRI fit of the femoral trabeculae was 53%±10%,and at the level of the superior horizontal rim of the tibial plateau epiphysis,the CT and MRI fit of the tibial trabeculae was 55%±6%.Conclusions:At 7.0 T MRI,SWI was able to show the cortical thickness of the posterior portion of the femur of the knee more accurately,but there were some limitations in the display of trabecular bone structure.
bone microstructureultra-high-resolution CT7.0 Tmagnetic resonance imagingsusceptibility weighted imaging
万方数据
维普
