Research progress of multimodal MRI in tremor-dominant Parkinson's disease
Parkinson's disease(PD)is the second most prevalent neurodegenerative disorder,typified by resting tremors,bradykinesia,rigidity,and postural instability.The tremor-dominant(TD)subtype of PD is characterized mainly by limb tremors,which severely impact the quality of life in advanced TD-PD patients.Advances in magnetic resonance imaging(MRI)techniques have provided several non-invasive scientific methods for studying brain structure and function in TD-PD.This paper discusses the structural and functional aspects of the brain,reviewing the progress in multimodal MRI techniques such as three-dimensional T1-weighted imaging(3D-T1WI),diffusion tensor imaging(DTI),blood oxygenation level-dependent(BOLD)imaging,susceptibility-weighted imaging(SWI),magnetic resonance spectroscopy(MRS),and neuromelanin-sensitive MRI(NM-MRI)in TD-PD patients,offering new insights for future research.
Parkinson's diseasetremormagnetic resonance imagingstructural magnetic resonance imagingfunctional magnetic resonance imaging
万方数据
维普
