超高场磁共振成像(ultra-high-field magnetic resonance imaging,UHF-MRI)作为一项前沿技术,凭借卓越的信噪比(signal-to-noise ratio,SNR)和分辨率广受关注.7 T磁共振成像(magnetic resonance imaging,MRI)作为其中的典型代表,已开始从科研走向临床,在包括高分辨率结构成像、磁敏感成像、多核成像、波谱和血氧水平依赖等磁共振技术方面取得诸多变革,极大提高了神经系统疾病的诊断能力.然而,磁场强度的增加也带来了射频场不均匀性增强、比吸收率增高等多方面的考验.这些考验可能会加剧图像伪影,限制特定成像序列的使用,影响UHF-MRI在临床的推广.本文根据陆军军医大学第一附属医院7 T MRI使用经验,结合相关文献,阐述了UHF-MRI的核心优势与面临的主要挑战,简要介绍了其在神经系统的优势和潜力,期望能为其他单位开展7 T MRI相关工作提供经验性探索.
Advantages and challenges of 7 T magnetic resonance imaging and typical clinical application for neurological disorders
Ultra-high-field magnetic resonance imaging(UHF-MRI),as a cutting-edge technology,has received widespread attention for its distinct advantages to both signal-to-noise ratio(SNR)and resolution.Recently,as the prototypical representative of UHF-MRI,7 T magnetic resonance imaging(MRI)has begun to move from scientific research to clinical practice,and has made many changes in magnetic resonance techniques,including high-resolution structural imaging,susceptibility weighted imaging,X-nuclei MRI,magnetic resonance spectroscopy and blood oxygen level dependent magnetic resonance,which have greatly improved the diagnosis of neurological diseases.However,the increase in magnetic field strength also brings some challenges,such as enhanced radio frequency field inhomogeneity and specific absorption ratio limitation.These problems may exacerbate image artifacts,limit the utility of certain imaging sequences,and affect the promotion of UHF-MRI in clinical practice.Based on the experience of using 7 T MRI in the First Affiliated Hospital of the Army Medical University,this paper discusses the core advantages and main challenges of UHF-MRI,and briefly introduces its potentials in neurological system in the light of relevant literature,with the expectation of providing empirical insights for others to conduct 7 T MRI related research.
ultra-high-fieldmagnetic resonance imagingneuroimagingneurological disease7 T magnetic resonance imaging
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