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消化道早期癌内窥镜黏膜下剥离术术后疼痛现状及影响因素分析

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目的 分析内窥镜黏膜下剥离术(ESD)治疗消化道早期癌术后疼痛的现状及其影响因素,为制定精准的疼痛干预方法、减轻术后疼痛、提高满意度、促进康复提供参考依据。方法 采用横断面调查法选取四川大学华西医院消化内科2019年5月至2023年6月收治的消化道早期癌患者313例为研究对象。收集患者的社会人口学资料、临床资料以及疼痛发生情况,采用单因素分析及多因素分析探讨消化道早期癌ESD术后疼痛的现状及影响因素。结果 消化道早期癌ESD术后疼痛的发生率为33。22%。单因素分析结果显示,疾病诊断、手术名称、手术部位、术后有无胃管、手术范围、手术时长、麻醉时长、术前有疼痛病史、术后有发热、术后有出血对ESD术后患者发生疼痛的影响差异有统计学意义(P<0。05)。二元Logistic回归分析结果显示,手术部位和华西心情指数(HEI)是ESD术后发生疼痛的独立危险因素(P<0。05)。不同手术部位疼痛分布不同,食管ESD术后疼痛好发于胸部,胃ESD术后疼痛好发于上腹部,肠ESD术后疼痛好发于下腹部。结论 诊断为食管恶性肿瘤、HEI评分越高、手术部位位于食管、麻醉时间和手术时间越长、术后有胃管、术前有疼痛病史、术后有发热及出血的消化道早期癌患者ESD术后更易发生疼痛。
Status Quo and Influencing Factors of Pain After Endoscopic Submucosal Dissection for Early Gastrointestinal Cancer
Objective To analyze the current situation and influencing factors of pain after endoscopic submucosal dissection(ESD)for early gastrointestinal cancer,and to provide a reference basis for formulating precise pain intervention methods in the future,reducing postoperative pain in patients,improving patient satisfaction,and promoting patient recovery.Methods A total of 313 patients with early digestive tract cancer admitted to the Department of Gastroenterology,West China Hospital of Sichuan University from May 2019 to June 2023 were selected by cross-sectional survey.The socio-demographic data,clinical data and pain occurrence of the patients were collected.Univariate analysis and multivariate analysis were used to study the current situation and influencing factors of pain after ESD for early digestive tract cancer.Results The incidence of postoperative pain after ESD for early gastrointestinal cancer was 33.22%.Univariate analysis results showed that patient diagnosis,surgical name,surgical site,postoperative gastric tube presence,surgical scope,surgical duration,duration of anesthesia,preoperative history of pain,postoperative fever,and postoperative bleeding had statistically significant differences in the occurrence of pain in patients after ESD(P<0.05).The results of binary Logistic regression analysis showed that the operation site and Huaxi emotional distress index(HEI)were independent risk factors for pain after ESD(P<0.05).The locations of pain occurrence were different in patients with different operation sites.The pain after esophageal ESD was prone to occur in the chest,the pain after gastric ESD was prone to occur in the upper abdomen,and the pain after intestinal ESD was prone to occur in the lower abdomen.Conclusion Patients with early gastrointestinal cancer diagnosed as esophageal malignancy,higher HEI score,the operation site located in the esophagus,longer anesthesia duration,longer surgical duration,postoperative gastric tube placement,preoperative history of pain,and postoperative fever and bleeding are more likely to suffer from pain after ESD.

Early gastrointestinal cancerEndoscopic submucosal dissectionPainInfluencing factor

陈俊旭、张小梦、张宗霞、陈恋、柳亚茹、任宏飞、张铭光

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四川大学华西医院 消化内科(成都 610041)

四川大学华西医院/成都上锦南府医院(成都 611730)

消化道早期癌 内窥镜黏膜下剥离术 疼痛 影响因素

2025

成都医学院学报
成都医学院

成都医学院学报

影响因子:0.933
ISSN:1674-2257
年,卷(期):2025.20(1)