Effect of Soft-Channel Minimally Invasive Surgery on Hypertensive Cerebral Hemorrhage
Objective To analyze the effect of soft-channel minimally invasive surgery on hypertensive cerebral hemorrhage.Methods A total of 104 patients with hypertensive cerebral hemorrhage admitted to the Department of Neurosurgery of the First Affiliated Hospital of Henan University of Science and Technology from January 2021 to February 2024 were selected as the study objects.They were divided into the soft channel group(soft-channel minimally invasive surgery,n=50)and the hard channel group(hard-channel minimally invasive surgery,n=54)according to different treatment regimens.Hematoma related indicators such as intraoperative aspiration volume of hematoma and volume ratio were compared between the two groups.Serum soluble triggering receptor expressed on myeloid cell-1(sTREM-1),aquaporin 4(AQP4)and cell fibronectin(cFN)levels before operation and 7 d after operation were compared between the two groups.The prognosis[assessed by Glasgow Outcome Scale(GOS)],neurological function[assessed by National Institutes of Health Stroke Scale(NIHSS)],and ability of daily living[assessed by Activity Of Daily Living Scale(ADL)]were compared between the two groups.Results Compared with the hard channel group,the soft channel group exhibited lower intraoperative aspiration volume of hematoma and volume ratio,and shorter time of postoperative hematoma emptying and cerebrospinal fluid returning to normal,with statistical significance(P＜0.05).On the 7th d after operation,the serum levels of sTREM-1,AQP4 and cFN in both groups decreased,and the above indicators in the soft channel group were lower than those in the hard channel group(P＜0.05).One month after surgery,the scores of GOS and ADL increased in both groups,and the scores in the soft channel group were higher than those in the hard channel group(P＜0.05).One month after surgery,the NIHSS score decreased in both groups,and the score in the soft channel group was lower than that in the hard channel group(P＜0.05).Conclusion Soft-channel minimally invasive surgery can improve hematoma absorption and reduce serum levels of sTREM-1,AQP4 and cFN in hypertensive cerebral hemorrhage patients.
万方数据
维普
