Progress on the Synthesis of the Thiazole Derivatives
The thiazole derivatives possess extensive biological activity and have been an important issue studied by the domestic and overseas researchers. The research progress on the synthesis of the thiazole derivatives is stated, such as Hantzsch, the reagents of periodide, isothiocyanate, solid resin, dicarbonyl compound, oxidizing reaction of aromatic aldehyde with amine, loaded reagent, etc. The advantage and disadvantage of some methods are pointed out. In the end, the prospect of their research orientations are forecasted.
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