Due to the advantages of high energy density,long cycle life,light weight,energy saving and environmental protection,and low self-dis-charge,lithium-ion batteries(LIBs)have been widely used in transportation engineering,aerospace,new energy,mechanical engineering and other industrial fields in recent years.However,LIBs are inevitably subjected to collision accidents during service,which results in internal short circuits and further induces thermal runaway,and even causes the catastrophic consequences of fire and explosion.Therefore,it is of great significance to study the mechanical-electrical-thermal response characteristics and safety prediction of LIBs under mechanical abuse.Firstly,the internal structures and engineering application of LIBs in this paper are introduced.The mechanical properties of LIBs under various mechanical abuses at home and abroad are reviewed,and the failure mechanisms of LIBs under different working conditions are also clarified.Secondly,from the perspective of crashworthiness and safety risk prediction,the latest research progress in the crashworthiness index and safety evaluation of LIBs is summarized.Finally,the future development prospects of LIBs under mechanical abuse and multi-physics coupling are discussed.The purpose of this paper can provide a theoretical basis for the integrated design of multi-functional structures of LIBs.