This paper takes the 1 000 MW ultra-supercritical coal-fired unit of a power plant in Guangdong as the ob-ject of study.On the basis of ensuring the safe operation of the unit,by optimizing the oxygen volume measurement,oxygen volume and total airflow curves,and automatic oxygen volume program,the ratio between the actual air vol-ume involved in combustion and the theoretically needed air volume is adjusted,to keep the combustion in its opti-mal state to obtain good economy.