重庆医学2024,Vol.53Issue(2) :264-269.DOI:10.3969/j.issn.1671-8348.2024.02.019

健康饮食模式对CKD患者死亡率、ESKD和CVD发生率影响的meta分析

Meta analysis of effects of healthy eating patterns on mortality,ESKD and CVD incidence in patients with CKD

李杨 彭红梅 黄霞 蒲诗 唐相春 石钰
重庆医学2024,Vol.53Issue(2) :264-269.DOI:10.3969/j.issn.1671-8348.2024.02.019

健康饮食模式对CKD患者死亡率、ESKD和CVD发生率影响的meta分析

Meta analysis of effects of healthy eating patterns on mortality,ESKD and CVD incidence in patients with CKD

李杨 1彭红梅 1黄霞 1蒲诗 1唐相春 1石钰1
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作者信息

  • 1. 陆军军医大学第二附属医院(新桥医院)肾内科CKD管理中心,重庆 400037
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摘要

目的 通过meta分析探讨健康饮食模式对慢性肾脏病(CKD)患者死亡率、终末期肾病(ESKD)发生率、心血管疾病(CVD)发生率的影响.方法 计算机检索PubMed、Embase、Cochrane Library、中国知网、万方数据库及维普数据库中关于健康饮食模式对CKD患者死亡率与ESKD、CVD发生率影响的研究,检索时间为建库至2023年1月.由两名研究者独立筛选文献和提取资料,并进行文献质量评价.采用RevMan5.3软件对纳入的文献进行meta分析.结果 本研究共纳入10篇文献,涉及27 291例患者.结果 显示,饮食评分高的患者与饮食评分低的患者在死亡率(HR=0.70,95%CI:0.57~0.87,Z=3.18,P=0.001)、ESKD发生率(HR=0.80,95%CI:0.71~0.91,Z=3.44,P<0.001)和 CVD 发生率(HR=0.77;95%CI:0.61~0.97,Z=2.21,P=0.003)方面比较均有差异.结论 坚持健康饮食模式会降低CKD患者死亡率、ESKD发生率和CVD发生率.

Abstract

Objective To investigate the impact of healthy eating patterns on the mortality rate and in-cidence rates of end-stage kidney disease(ESKD)and cardiovascular disease(CVD)in the patients with chronic kidney disease(CKD)by meta analysis.Methods The studies on the relationship between the dietary patterns on the mortality,and the incidence rates of ESKD and CVD in the patients with CKD were retrieved from PubMed,Embase,Cochrane Library,CNKI,Wanfang Database and VIP Database.The retrieval time was from the database establishment to January 2023.The two researchers independently screened the literatures,ex-tracted the data and conducted the literature quality evaluation.The RevMan5.3 software was used for the meta-analysis of the included literatures.Results A total of 10 studies were included in this study,involving 27 291 patients.The results showed that the mortality(HR=0.70,95%CI:0.57-0.87,Z=3.18,P=0.001)and the ESKD incidence rate(HR=0.80,95%CI:0.71-0.91,Z=3.44,P<0.001)and CVD inci-dence rate(HR=0.77;95%CI:0.61-0.97,Z=2.21,P=0.003)had statistical differences between the pa-tients with high dietary score and the patients with low dietary score.Conclusion Persisting in the healthy dieta-ry patterns could decrease the mortality rate,and incidence rates of ESKD and CVD in the patients with CKD.

关键词

慢性肾脏病/饮食模式/死亡率/终末期肾病/meta分析

Key words

chronic kidney disease/dietary patterns/mortality rate/end-stage kidney disease/meta analysis

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基金项目

重庆市科卫联合医学科研项目(2021MSXM313)

陆军军医大学第二附属医院护理培育项目(2022HLPY008)

出版年

2024
重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
参考文献量1
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