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瘦素与肺癌微环境的研究进展

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瘦素是一种由白色棕色脂肪组织分泌的细胞因子激素,参与细胞增殖、分化、凋亡及细胞因子分泌等过程。最新研究证实,瘦素与肺癌的发生与发展密切相关,瘦素可以通过调节免疫应答及神经内分泌来调控肺癌微环境。该文对瘦素在肺癌微环境中的作用和机制做一综述,旨在为肺癌的基础研究提供参考与借鉴。
Research progress of leptin and lung cancer microenvironment
Leptin is a cytokine hormone secreted by white and brown adipose tissue to participate in the processes of cell proliferation,differentiation,apoptosis,and cytokine secretion.The latest research confirms that leptin is closely correlated with the occurrence and development of lung cancer.Lepdin can regulate the microenvironment of lung cancer by regulating immune response and nerve endocrine.This article reviews the role and mechanism of leptin in the microenvironment of lung cancer,aiming to provide reference for basic re-search on lung cancer.

leptinlung cancermicroenvironmentreview

张彩兰、王蓓

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山西医科大学第二医院呼吸内科,太原 030001

瘦素 肺癌 微环境 综述

山西省医学重点攻关专项项目

2022XM29

2024

重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
年,卷(期):2024.53(2)
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