首页|BRAF V600E突变非小细胞肺癌患者全程管理的研究进展

BRAF V600E突变非小细胞肺癌患者全程管理的研究进展

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肺癌是全球发病及死亡人数最多的恶性肿瘤,其中以非小细胞肺癌(NSCLC)占比最多。鼠类肉瘤病毒癌基因同源物B1(BRAF)是一种原癌基因,与NSCLC的不良预后有关,其中以BRAF V600E突变为代表。近年来,关于BRAF V600E突变NSCLC患者的诊治已成为肺癌精准诊疗研究的焦点,特别是其全程管理备受关注。关于BRAF V600E突变患者的靶向、免疫及化疗等的相关研究层出不穷,该文就国内外相关的研究进展进行综述。
Research progress on whole-course management of non-small cell lung cancer patients with BRAF V600E mutation
Lung cancer is the malignant tumor with the highest incidence and death in the world,among which non-small cell lung cancer(NSCLC)accounts for the largest proportion.The BRAF gene is a proto-on-cogene associated with poor prognosis in NSCLC,represented by BRAF V600E mutations.In recent years,the diagnosis and treatment of NSCLC patients with BRAF V600E mutation has become the focus of accurate di-agnosis and treatment of lung cancer,especially its whole-course management.There are many related studies on targeting,immunotherapy and chemotherapy for patients with BRAF V600E mutation.This paper reviewed the relevant research progress at home and abroad.

non-small cell lung cancerBRAF V600Etreatmentwhole-course managementreview

杨淋、王玉波

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重庆大学附属江津医院呼吸与危重症医学科,重庆 402260

非小细胞肺癌 BRAF V600E 治疗 全程管理 综述

重庆市区域医学重点学科项目

zdxk201701

2024

重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
年,卷(期):2024.53(5)
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