首页|基于列线图的结直肠癌影响因素分析

基于列线图的结直肠癌影响因素分析

扫码查看
目的 通过了解结直肠癌发病相关影响因素,构建列线图,更好地识别结直肠癌危险人群。方法 选取2020年10月至2023年3月四川省7家医疗机构半年内确诊为结直肠癌的368例患者作为病例组,选取同期体检的380例一般人群作为对照组,对其进行问卷调查,采用多因素logistic回归分析结直肠癌相关影响因素,构建结直肠癌影响因素列线图,对模型进行内部验证,评估稳定性。结果 多因素logistic回归分析结果显示,农民(OR=3。527,95%CI:1。451~8。576)、偏好动物油(OR=3。789,95%CI:1。270~11。251)、含糖饮料(OR=1。921,95%CI:1。200~3。075)、不吃钙片(OR=2。011,95%CI:1。311~3。085)会增加结直肠癌发生危险;个人年收入越高(OR=0。482,95%CI:0。288~0。808;OR=0。126,95%CI:0。053~0。299)、没有肠道息肉(OR=0。169,95%CI:0。104~0。274)、不吃重油脂食物(OR=0。432,95%CI:0。272~0。688)、轻度体力劳动(OR=0。220,95%CI:0。122~0。397)会降低结直肠癌发生危险。列线图准确率为74。3%,受试者工作特征(ROC)曲线下面积为0。836,模型具有良好区分度和可靠性。结论 列线图可视化肠癌影响因素,利于其防治工作开展。
Analysis of influencing factors of colorectal cancer based on nomogram
Objective To better identify the risk population of colorectal cancer by understanding the related influencing factors of colorectal cancer and constructing nomogram.Methods From October 2020 to March 2023,a total of 368 patients diagnosed with colorectal cancer in seven medical institutions in Sichuan Province were selected as the case group,and 380 general people in the same period were selected as the con-trol group.The questionnaire survey was conducted,and the related influencing factors of colorectal cancer were analyzed by multivariate logistic regression,and the nomogram of influencing factors of colorectal cancer was constructed.The model was verified internally,and its stability was evaluated.Results The results of multivariate logistic regression analysis showed that farmers (OR=3.527,95%CI:1.451-8.576),preference for animal oil (OR=3.789,95%CI:1.270-11.251),sugary drinks (OR=1.921,95%CI:1.200-3.075), and not taking calcium tablets (OR=2.011,95%CI:1.311-3.085) increased the risk of colorectal cancer;higher annual personal income (OR=0.482,95%CI:0.288-0.808;OR=0.126,95%CI:0.053-0.299),ab-sence of intestinal polyps (OR=0.169,95%CI:0.104-0.274),no heavy fatty foods (OR=0.432,95%CI:0.272-0.688),and light physical work (OR=0.220,95%CI:0.122-0.397) would reduce the risk of color-ectal cancer.The accuracy of nomogram was 74.3%,and the area under the receiver operating characteristic (ROC) curve was 0.836,the model had good discrimination and reliability.Conclusion The Nomogram can visualize influencing factors of colorectal cancer,which is beneficial to its prevention and treatment.

colorectal cancercase-control studyanalysis of influencing factorslogistic regressionnomogram

李玉婷、王青青、易芳、杨中华、张铃林、容丽楼、李菊、万绍平

展开 >

成都中医药大学公共卫生学院,成都 611137

四川省肿瘤临床医学研究中心/四川省肿瘤医院·研究所/四川省癌症防治中心/电子科技大学附属肿瘤医院科技处,成都 610041

结直肠癌 病例对照研究 影响因素分析 logistic回归 列线图

四川省科技厅对口科技援助项目

2021YFQ0032

2024

重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
年,卷(期):2024.53(6)
  • 26