Diagnostic value of diffusion tensor imaging combined with diffusion tensor tractography in cervical spondylotic myelopathy
Objective To investigate the diagnostic value of diffusion tensor imaging (DTI) combined with diffusion tensor tractography (DTT) in patients with cervical spondylotic myelopathy (CSM).Methods A prospective study was conducted on 20 CSM patients (the CSM group) who underwent surgery and 20 healthy volunteers (the control group).The subjects underwent routine MRI examination and DTI scan of the cervical spine,then the images were post-processed,and the corresponding parameter values of DTI and DTT were recorded,including fraction anisotropy (FA),average diffusion coefficient (DC-avg) and diffusion tensor tractography density (DTT-density).The score of the Japanese Orthopaedic Association (JOA) and the de-gree of spinal cord compression of all CSM patients were recorded,and the CSM patients were graded accord-ing to the JOA score.According to the degree of compression degree of spinal cord and JOA score,they were divided into the imaging typical performance group and atypical performance group.The DTI and DTT param-eters between the patients of the CSM group and the healthy volunteers of the normal control group were compared,and the correlation between DTI and DTT parameters and JOA score of CSM patients in the ima-ging typical and atypical performance groups was analyzed by Pearson and Spearman correlation analysis.Re-sults The values of FA and DTT-density (except for the values of FA and DTT-density in C1/2 and DC-avg and DTT-density in C7/T1) in the CSM group were significantly lower than those in the control group,and the values of DC-avg were significantly higher than those in the control group,with statistical significance (P<0.05).The values of FA,DC-avg and DTT-density (except for the values of C3/4 and C6/7 DTT-density) in the CSM group were significantly different from those in the control group (P<0.05).The degree of spinal cord compression was correlated with the JOA score in the imaging typical performance group (P<0.05),while the JOA score in the imaging atypical performance group was not correlated with the degree of spinal cord compression (P>0.05).The values of FA,DC-avg and DTT-density were correlated with JOA scores of pa-tients in the imaging typical and atypical performance groups (P<0.05).Conclusion In the preoperative di-agnosis of CSM patients,the values of FA,DC-avg and DTT-density are closely related to the JOA score of pa-tients,which can effectively judge the actual nerve injury of patients.
万方数据
维普
