Effect of prone position ventilation on respiratory function in premature infants born at 28 weeks of gestational age or more
Objective To investigate the effect of prone position ventilation on respiratory function of premature infants ≥ 28 weeks of gestational age.Methods From June 1,2021 to January 31,2022,a total of 75 premature infants ≥ 28 weeks of gestational age who needed ventilator support (including invasive and non-invasive ventilation) due to respiratory dysfunction in the pediatrics department of the hospital were se-lected as the research subjects.They were randomly divided into the supine position group (41 cases) and prone position group (34 cases).The prone position group had two hours of prone position ventilation in the treatment unit every eight hours,and the rest of the interventions were the same as the supine position group, and the cycle operation was performed until weaning.Lung ultrasound score (LUSsc) was performed on all subjects at <24 h,24-<48 h,48-<72 h and 72-<96 h after birth,and related clinical parameters such as respiratory support and related complications of premature infants were collected.Results The 1st-3rd LUSsc was positively correlated with the neonatal emergency physiology score-Ⅱ (SNAP-Ⅱ,P<0.05),and the 2nd-4th LUSsc was positively correlated with the total duration of respiratory support,total duration of oxygen inhalation and home oxygen therapy (P<0.05).Compared with LUSsc in the same group at different time,the difference was statistically significant (P<0.05).Compared with the prone supine group,LUSsc of the supine position group was higher in the 2nd-4th time,and the difference was statistically significant (P<0.05).There was no statistical difference in the incidence of late neonatal septicemia (LOS),intraventricular hemorrhage (IVH),extrauterine growth restriction (EUGR),feeding intolerance (FI) and neonatal necrotiz-ing enterocolitis (NEC) between the two groups (P>0.05).Conclusion Prone position ventilation can pro-mote the absorption of lung lesions in premature infants with gestational age ≥ 28 weeks,improve their re-spiratory function,and do not increase the risk of complications and adverse events.
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