Clinical application effect of oropharyngeal muscle training combined with pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis complicating obstructive sleep apnea
Objective To explore the clinical application effect of oropharyngeal muscle training com-bined with pulmonary rehabilitation in the patients with idiopathic pulmonary fibrosis and obstructive sleep apnea(IPF-OSA).Methods Fifty patients with IPF-OSA admitted and treated in Chengdu Municipal Hospi-tal of Integrated Traditional Chinese and Western Medicine from February 2020 to April 2023 were selected as the study subjects.The enrolled patients were given the breathing training twice a day,exercise training three times a week,and oropharyngeal muscle training twice a day.The blood gas analysis,6 min walking distance,pulmonary function,respiratory muscle strength test,apnea hypopnea index(AHI),fatigue questionnaire score and and St.George's questionnaire scores in the patients were compared between before intervention and in 2 months after intervention.Results The maximal inspiratory pressure(MIP),maximal expiratory pres-sure(MEP),6 min walking distance,AHI,oxygen desaturation index,oxygen desaturation time,lowest mean oxyhemoglobin saturation,mean arterial oxyhemoglobin saturation,forced vital capacity(FVC),forced expira-tory volume in the first second(FEV1),fatigue questionnaire score and St.George's questionnaire scores had statistical difference between before intervention and after intervention(P＜0.05).The correlation analysis showed that FVC was positively correlated with MIP,MEP and 6 min walking distance(r=0.697,0.638,0.629,P＜0.05),and negatively correlated with the fatigue questionnaire score and St.George's questionnaire scores(r=-0.610,-0.805,P＜0.05);FEV1 was positively correlated with MIP,MEP and 6 min walking distance(r=0.425,0.739,0.421,P＜0.05),and negatively correlated with the fatigue questionnaire score and St.George's questionnaire scores(r=-0.434,-0.760,P＜0.05).Conclusion The oropharyngeal mus-cle training combined with pulmonary rehabilitation could improve the hypoxia status of the patients,increase the exercise endurance and improve the quality of life.
国家科技期刊平台
NSTL
万方数据
