首页|免疫炎症与降低血压的相关研究进展

免疫炎症与降低血压的相关研究进展

Research progress on correlation between immune inflammation and blood pressure reduction

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免疫炎症与血压的调控相关,众多临床研究发现通过免疫抑制、抗炎疗法可以降低血压,但通过免疫炎症降压的具体途径尚不清楚.该文归纳了非药物抗炎,以及干预不同免疫细胞、炎症小体和炎症基因对血压的影响,总结了不同途径降压的效果及其对靶器官的影响.对于传统方式降压无法达到满意效果的高血压,也许可以通过免疫抑制、抗炎治疗控制血压,减轻靶器官的损伤,为降低血压提供新的研究思路.
Immune inflammation is correlated to the regulation of blood pressure,and many clinical studies have found that the immunosuppression and anti-inflammatory therapy can decrease blood pressure,but the specific way to lower blood pressure through immune inflammation is still unclear.This article sum-marizes the effects of non-drug anti-inflammatory,intervention of different immune cells,inflammasomes and inflammatory genes on blood pressure,and summarizes the effects of different pathways on lowing blood pres-sure.For hypertension that cannot achieve satisfactory results by traditional antihypertensive treatment,im-munosuppression and anti-inflammatory therapy may be used to control blood pressure and reduce the damage of target organs,so as to provide the new research ideas for lowering blood pressure.

hypertensionimmune cellsinflammasomesinflammatory genesanti-inflammatoryre-view

蒙妮、李文俊、姬燕梅、郭妮、金醒昉

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昆明市延安医院:心内科,昆明 650051

昆明市延安医院:心外科,昆明 650051

高血压 免疫细胞 炎症小体 炎症基因 抗炎 综述

国家自然科学基金项目云南省科技厅中央引导地方发展资金项目云南省肿瘤免疫防治重点实验室项目

81460209202307AB1100052017DG004-01

2024

重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
年,卷(期):2024.53(7)
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