Immune inflammation is correlated to the regulation of blood pressure,and many clinical studies have found that the immunosuppression and anti-inflammatory therapy can decrease blood pressure,but the specific way to lower blood pressure through immune inflammation is still unclear.This article sum-marizes the effects of non-drug anti-inflammatory,intervention of different immune cells,inflammasomes and inflammatory genes on blood pressure,and summarizes the effects of different pathways on lowing blood pres-sure.For hypertension that cannot achieve satisfactory results by traditional antihypertensive treatment,im-munosuppression and anti-inflammatory therapy may be used to control blood pressure and reduce the damage of target organs,so as to provide the new research ideas for lowering blood pressure.