免疫炎症与降低血压的相关研究进展
Research progress on correlation between immune inflammation and blood pressure reduction
蒙妮 1李文俊 2姬燕梅 1郭妮 1金醒昉1
作者信息
- 1. 昆明市延安医院:心内科,昆明 650051
- 2. 昆明市延安医院:心外科,昆明 650051
- 折叠
摘要
免疫炎症与血压的调控相关,众多临床研究发现通过免疫抑制、抗炎疗法可以降低血压,但通过免疫炎症降压的具体途径尚不清楚.该文归纳了非药物抗炎,以及干预不同免疫细胞、炎症小体和炎症基因对血压的影响,总结了不同途径降压的效果及其对靶器官的影响.对于传统方式降压无法达到满意效果的高血压,也许可以通过免疫抑制、抗炎治疗控制血压,减轻靶器官的损伤,为降低血压提供新的研究思路.
Abstract
Immune inflammation is correlated to the regulation of blood pressure,and many clinical studies have found that the immunosuppression and anti-inflammatory therapy can decrease blood pressure,but the specific way to lower blood pressure through immune inflammation is still unclear.This article sum-marizes the effects of non-drug anti-inflammatory,intervention of different immune cells,inflammasomes and inflammatory genes on blood pressure,and summarizes the effects of different pathways on lowing blood pres-sure.For hypertension that cannot achieve satisfactory results by traditional antihypertensive treatment,im-munosuppression and anti-inflammatory therapy may be used to control blood pressure and reduce the damage of target organs,so as to provide the new research ideas for lowering blood pressure.
关键词
高血压/免疫细胞/炎症小体/炎症基因/抗炎/综述Key words
hypertension/immune cells/inflammasomes/inflammatory genes/anti-inflammatory/re-view引用本文复制引用
基金项目
国家自然科学基金项目(81460209)
云南省科技厅中央引导地方发展资金项目(202307AB110005)
云南省肿瘤免疫防治重点实验室项目(2017DG004-01)
出版年
2024
国家科技期刊平台
NSTL
万方数据