首页|风险评估指标在多重耐药菌感染防控早期的运用

风险评估指标在多重耐药菌感染防控早期的运用

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目的 分析多重耐药菌感染防控初期的风险因素,寻找早期干预的主要风险评估指标,降低患者多重耐药菌的感染率和死亡率。方法 通过回顾性分析该院2022年出院的238例ICU多重耐药菌感染患者病史,得到4项多重耐药菌感染相关共性风险评估指标,运用SPSST统计软件,验证正态分布后,开展指标间相关性分析,并使用二元logistic回归分析,证实指标选择的可靠性。结果 各项指标经描述分析检验符合正态分布,采用皮尔逊双尾法对死亡与年龄段、隔离医嘱、首次治疗性抗菌药物使用前微生物送检、基础疾病4项风险评估指标进行相关性分析,在95%置信区间(95%CI)下P<0。05,有显著相关性。用二元logistic回归验证:以"死亡"为因变量,年龄段、隔离医嘱、首次治疗性抗菌药物使用前微生物送检、基础疾病为自变量,P<0。001,显示该模型构建有效。结论 针对这4项指标的早期评估对临床前瞻性提示、规范诊疗行为有积极作用。
Application of risk assessment indicators in early prevention and control of multidrug-resistant bacterial infections
Objective To analyze the risk factors in the early prevention and control of multidrug-re-sistant bacterial infections,and to seek the main risk assessment indicators for early intervention in order to reduce the infection rate and mortality rate of multidrug resistant bacteria in the patients.Methods A retro-spective analysis was conducted on the medical histories of 238 ICU patients with multidrug-resistant bacterial infections discharged from a tertiary comprehensive hospital in Shanghai during 2022.The 4 common risk as-sessment indicators related to multidrug-resistant bacterial infections were obtained.The SPSST statistical software was used to verify the normal distribution,and the correlation analysis among the indicators was con-ducted.The binary logistic regression analysis was used to confirm the reliability of indicator selection. Results All indicators were tested by the descriptive analysis to conform to a normal distribution.The Pear-son's two tailed method was used to conduct the correlation analysis on the death with 4 risk assessment indi-cators of the age,isolation doctor's order,microbiological submitted examination before the first use of thera-peutic antibiotic drugs and basic diseases,which had significant correlation in 95% confidence interval (CI) (P<0.05).The binary logistic regression was used to verify that "death" was the dependent variable,the age group,isolation doctor's order,microbial submitted examination before the first use of therapeutic antibiotic drugs and underlying diseases were the independent variables,P<0.001,indicating that the model construc-tion was effective.Conclusion The early evaluation aiming at these 4 indicators has a positive effect on clinical prospective tips and standardized diagnosis and treatment behavior.

infection with multidrug-resistant bacteriarisk assessment indicatorsICUinfection prevention and control

朱炳蔚、肖钰瑜

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同济大学附属东方医院医院感染管理科,上海 200120

多重耐药菌感染 风险评估指标 ICU 感染防控

上海市卫生健康委卫生健康政策研究课题上海市浦东新区卫生系统特色专病建设项目

2023HP56PWZzb2022-23

2024

重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
年,卷(期):2024.53(8)
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