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先天性巨结肠相关性小肠结肠炎的危险因素分析

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目的 探讨先天性巨结肠相关性小肠结肠炎(HAEC)的危险因素,为先天性巨结肠(HSCR)的诊治提供依据,为减少术后并发症的发生及患儿的术后康复提供指导。方法 回顾性分析2015年1月至2023年1月该院小儿普外科收治的HSCR且初次手术治疗的110例患儿病例资料,分析HAEC发生的危险因素。结果 110例患儿中34例发生HAEC,发生率为30。91%。HAEC患儿不同年龄、术前洗肠时间、术前发生肠炎、低体重、病变痉挛段长度、饮食控制情况比较,差异有统计学意义(P<0。05)。多因素logistic回归分析结果显示,年龄≥6岁(OR=2。407,95%CI:1。040~5。568)、术前洗肠时间<2周(OR=2。464,95%CI:1。082~5。612)、术前发生肠炎(OR=2。943,95%CI:1。193~7。260)、低体重(OR=2。588,95%CI:1。113~6。014)、病变痉挛段长度≥30 cm(OR=2。801,95%CI:1。224~6。412)是HAEC发生的危险因素(P<0。05),饮食控制(OR=0。358,95%CI:0。153~0。837)是HAEC发生的保护因素(P<0。05)。结论 HSCR患儿术后应针对HAEC发生的危险因素进行预防。
Analysis of risk factors for Hirschsprung's associated enterocolitis
Objective To investigate the risk factors of Hirschsprung's associated enterocolitis (HAEC) to provide a basis for the diagnosis and treatment of Hirschsprung's disease (HSCR),and offer the guidance for reducing the postoperative complications occurrence and postoperative rehabilitation. Methods The case data of the children patients with HSCR treated by initial surgery in the pediatric surgery department of this hospital from January 2015 to January 2023 were analyzed retrospectively.The risk factors of HAEC occurrence were analyzed.Results Among 110 children patients with HSCR,34 cases developed HAEC with a incidence rate of 30.91%.There were statistical differences in different ages,preoperative enter-itis occurrence,low body weight,length of spastic segment of lesion and diet control (P<0.05).The multiva-riate logistic regression analysis results showed that the age ≥6 years old (OR=2.407,95%CI:1.040-5.568),preoperative bowel washing time<2 weeks (OR=2.464,95%CI:1.082-5.612),preoperative enter-itis occurrence (OR=2.943,95%CI:1.193-7.260),low body weight (OR=2.588,95%CI:1.113-6.014),and the length of spastic segment of lesion ≥30 cm (OR=2.801,95%CI:1.224-6.412) were the risk fac-tors of HAEC occurrence (P<0.05),while dietary control (OR=0.358,95%CI:0.153-0.837) was the pro-tective factor for HAEC (P<0.05).Conclusion Prevention after operation in the children patients with HSCR should be carried out according to the risk factors of HAEC occurrence.

childrenHirschsprung's diseaseHirschsprung's associated enterocolitisrisk factorscomplication

梁鹏、樊珈榕、李万富

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新疆医科大学第一附属医院小儿普外科,乌鲁木齐 830000

儿童 先天性巨结肠 先天性巨结肠相关性小肠结肠炎 危险因素 并发症

新疆维吾尔自治区区域协同创新专项(科技援疆计划)

2020E0267

2024

重庆医学
重庆市卫生信息中心,重庆市医学会

重庆医学

CSTPCD
影响因子:1.797
ISSN:1671-8348
年,卷(期):2024.53(8)
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