Effect of flurbiprofen axetil on perioperative body temperature and shivering in patients undergoing radical gastrectomy
Objective To investigate the effect of flurbiprofen axetil on perioperative body temperature and shivering in the patients undergoing radical gastrectomy.Methods A total of 120 patients with ASA grade Ⅱ or Ⅲ who underwent radical gastrectomy and entered the recovery room after operation from January to August 2022 were selected.The patients were divided into the flurbiprofen axetil group (F group) and con-trol group (C group) by the random number table method,60 cases in each group.The group F was intrave-nously infused by flurbiprofen axetil 100 mg (10 mL) after anesthesia induction,and the group C was intrave-nously infused after anesthesia induction.The general data of the patients were collected.The blood pressure,heart rate,mean arterial pressure and eardrum temperature of the patients were records before operation (T0),entering the recovery room (T1) and leaving the recovery room (T2).The number,intensity grade and duration of chills after entering the recovery room were evaluated.The VAS scores and adverse reactions such as nausea and vomiting were recorded at 10 min (T3 ) and 30 min (T4) after extubation.Results Compared with at T0,the eardrum temperature of the two groups at T1 and T2 was significantly decreased (P<0.05). There was no significant difference in ear temperature at T1 and T2 between the two groups (P>0.05).Com-pared with the control group,the incidence of shivering was significantly improved and the intensity was light-er in the F group (P<0.05).However,there was no statistically significant difference in the duration of shiv-ering (P>0.05).The VAS scores at T3 and T4 in the group F were significantly lower than those in the group C (P<0.05).There was no statistically significant difference in the incidence rate of postoperative nausea and vomiting between the two groups (P>0.05).Conclusion Flurbiprofen axetil could improve the occurrence of postoperative pain and shivering in the patients with radical gastrectomy,but does not affect the occurrence of perioperative hypothermia.
flurbiprofen axetilhypothermiashiveringperioperative period
万方数据
维普
