Analysis on clinical characteristics of 10 cases of chlamydia psittaci pneumonia
Objective To analyze the clinical characteristics of chlamydia psittaci pneumonia so as to in-crease the clinical doctor's early diagnosis and early treatment level to this disease.Methods The clinical data of 10 patients with chlamydia psittaci pneumonia diagnosed by metagenomic next-generation sequencing (mNGS) in the Affiliated Jiangjin Hospital of Chongqing University from March 2020 to April 2022 were ret-rospectively analyzed.The basic situation,clinical manifestations,laboratory detection[WBC,lymphocytes count (LYM),neutrophile granulocyte ratio,C reactive protein (CRP),procalcitonin (PCT),erythrocyte sedi-mentation rate (ESR),Fe2+,AST,ALT,brain natriuretic peptide (BNP),urine albumin],imageologic mani-festations,mNGS detection result,treatment and outcome were collected and summarized .Results Among 10 patients with chlamydia psittaci pneumonia,6 cases were males and 4 cases were females with a median age of 57.5 years old.The main manifestations were fever in 10 cases (high fever in 5 cases),cough in 7 cases,rel-atively slow pulse in 7 cases,headache in 5 cases and phlegm in 4 cases.80％ of the cases had a clear contact history of birds or poultry.WBC was normal in 8 cases,LYM was decreased in 7 cases,neutrophile granulo-cyte ratio was increased in 8 cases,CRP was increased in 9 cases (5 cases>200 mg/L),PCT was normal in 6 cases and blood Fe2+decrease was in 10 cases.The lungs in 9 cases showed solid shadow with blurred edges,and 1 case showed anti-halo sign,the lesions in all cases involved in the pleura,but only 3 cases had pleural ef-fusion.Bronchoalveolar lavage fluid (BALE) in 10 cases all served as specimen.Chlamydia psittaci sequences were detected by mNGS,and all cases were treated with quindones,azithromycin and other antibiotics and were discharged with improvement.Conclusion Chlamydia psittaci pneumonia has fever,moreover most of the first symptoms are fever,in addition to respiratory symptoms,the extrapulmonary manifestations are com-mon,there is birds or poultry contact history before onset and the typical imaging changes could prompt the diagnosis,collecting bronchoalveolar lavage fluid for mNGS detection as soon as possible,and early diagnosis could be clarified as early as possible.
万方数据
维普
