Objective To investigate the awareness of contrast-induced nephropathy(CIN)among medical staffs engaging in the vascular interventional work so as to provide a basis for effective prevention of CIN.Methods The questionnaire was designed by the literature review,expert interviews and research group discussions.The network survey on the CIN awareness was performed among the vascular interventional med-ical staffs in 141 hospitals across the country from May to June 2023 by using convenience sampling.Results A total of 325 medical staffs participated in the survey,and their awareness rate on three guidelines for the prevention of CIN at home and abroad was 20.31%-48.31%,and the awareness rate on the guidelines in doctors(73.44%)was higher than that in nurses(58.62%),and the difference was statistically significant(P<0.05).Fifty-five respondents(16.92%)were very familiar with the concept of CIN,eighty-three re-spondents(25.54%)did not know at all;sixty-four respondents(19.69%)were very aware of the risk factors of CIN,and eighty-two respondents(25.23%)were not aware at all.There were statistically significant differences in the cognition of CIN and its high-risk factors among the respondents with different positions,working years,educational background and professional titles(P<0.05).Conclusion The vascular interven-tional medical staffs have insufficient understanding of CIN prevention related guidelines,CIN concept and re-lated high-risk factors,so it is recommended that all units strengthen the relevant on-the-job training.