A meta analysis on influence of surgical site infection occurrence in colorectal cancer patients based on body mass index in Chinese population
Objective To systematically evaluate the effect of the body mass index(BMI)≥24 kg/m2 on the incidence rate of surgery site infection(SSI)in the Chinese patients with colorectal cancer.Methods The domestic and foreign databases were searched for the observational studies on SSI of colorectal cancer containing the single factor analysis and BMI.The literatures with BMI≥24 kg/m2 and the Chinese pa-tients with colorectal cancer as the study subjects were screened out.The literatures meeting the requirements performed the meta analysis and bias analysis.Results A total of 32 literatures were included with 10 350 pa-tients,among them,SSI occurred in 1 748 patients.There was significant heterogeneity among 32 literatures(I2=65％,P＜0.01).The random effects model was used for conducting the meta analysis,and the results showed that the incidence rate of SSI in colorectal cancer patients with BMI≥24 kg/m2 was higher than that in colorectal cancer patients with BMI＜24 kg/m2(OR=2.57,95％CI:2.07-3.19,P＜0.01).The funnel plot suggested that there was the publication bias in 7 literatures,and the Egger's test showed P=0.158,sug-gesting that the bias was not significant.Conclusion In the Chinese population,the incidence rate of SSI in the colorectal cancer patients with BMI≥24 kg/m2 is 2.57 times of that in the patients with BMI＜24 kg/m2.
colorectal cancersurgical site infectionbody mass indexChinese populationmeta analysis
万方数据
维普
