Analgesic effect of different administration time of compound lidocaine cream for lumbar paracentesis in infants＜3 months old
Objective To investigate the analgesic effect of different administration times of compound lidocaine cream for lumbar paracentesis in the infants＜3 months oldMethods A total of 120 infants with lumbar puncture in the pediatric department of this hospital from January 2021 to June 2023 were selected as the study subjects and divided into the control group and observation 1,2,3 groups according to the random number table method,30 cases in each group.The control group had no medication intervention in the punc-ture local part before lumbar paracentesis,while the observation 1,2,3 groups were smeared the compound li-docaine cream 0.5 g,5 cm2 with the puncture point as the center at 10,30,60 min before lumbar puncture.The change situation of the Neonatal Infant Pain Scale(NIPS)score,heart rate(HR)and transcutaneous blood oxygen saturation(SpO2)at 1 min before puncture,1 min of puncture beginning and 3 min after puncture and the puncture success rate were compared among 4 groups.Results Compared with at 1 min before puncture,the NIPS score at 1 min of puncture beginning and at 3 min after puncture in 4 group was higher,the NIPS score at 1 min of puncture beginning and at 3 min after puncture in the observation 1,2,3 groups was lower than that in the control group,moreover the observation 2,3 groups were lower the observation 1 group(P＜0.05).Compared with at 1 min before puncture,except the heart rate at 3 min after puncture in the observa-tion 3 group was slower,the heart rate at other time points in the 4 groups was faster(P＜0.05);HR at 1 min of puncture beginning and at 3 min after puncture in the observation 1,2,3 groups was slower than that in the control group,moreover the observation 2,3 groups was lower than the observation 1 group(P＜0.05),SpO2 had no statistical difference among 4 groups(P＞0.05).The puncture success rate in the observation 1,2,3 groups was higher than that in the control group(P＜0.05).Conclusion Smearing compound lidocaine cream before lumbar puncture in the infants＜3 months old has a good analgesic effect and could increase the success rate of puncture.
万方数据
维普
