Rehabilitation efficacy of repetitive transcranial magnetic stimulation combined with cognitive behavioral therapy in Parkinson's disease complicating depression
Objective To investigate the effect of repetitive transcranial magnetic stimulation(rTMS)combined with the cognitive behavioral therapy(CBT)on the rehabilitation efficacy of the patients with Par-kinson's disease complicating depression(dPD).Methods Seventy patients with dPD in the Nanning Munici-pal Fifth People's Hospital from February 2020 to February 2023 were selected as the study subjects and di-vided into the observation group and control group according to the random number table method,35 cases in each group.Three cases in the control group during the study period came off.The control group was given the rTMS treatment,while the observation group was treated by rTMS+CBT.The remission situations of de-pressive symptoms before treatment,in 4,16 weeks after treatment were compared between the two groups.The Hamilton Depression Scale(HAMD),Social Disability Screening Schedule(SDSS)and Automatic Think-ing Questionnaire(ATQ)were used to evaluate the improvement effect of depression degree,negative auto-matic thinking and social function.Results There were statistically significant differences in the treatment mode,time factor and the interaction between time and treatment mode in HAMD,SDSS and ATQ scores be-tween the two groups(P＜0.05).The one-way ANOVA results revealed that the HAMD,SDSS and ATQ scores in the two groups were in turn decreased with the treatment time extension(P＜0.05).The multivari-ate ANOVA analysis results demonstrated that the HAMD,SDSS and ATQ scores in 4,16 weeks after treat-ment in the observation group were lower than those in the control group(P＜0.05).Conclusion rTMS+CBT for treating dPD has significant anti-depression effect,improves the negative thinking and increases the social function.
Parkinson's diseasedepressionrepetitive transcranial magnetic stimulationcognitive be-havioral therapyanti-depression treatment
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维普
