Esophageal carcinoma is one of the most common malignant cancer of the digestive system and an important cause of cancer death worldwide.Esophageal squamous cell carcinoma is the most common pathological type of esophageal cancer in China,but its pathogenesis has not been completely clarified.With the in-depth study of long non-coding RNA(lncRNA),it has been found that lncRNA can be used as an im-portant biomarker to directly or indirectly regulate the expression of downstream genes in multiple physiologi-cal processes such as transcription and post-transcriptional regulation,thereby regulating the malignant pro-gression of esophageal squamous cell carcinoma.This article reviews the research progress of lncRNA in the early diagnosis,prognosis regulation,radiochemotherapy sensitivity,invasion and migration of esophageal squamous cell carcinoma.
关键词
长链非编码RNA/食管癌/食管鳞状细胞癌/生物标志物/肿瘤调控
Key words
long non-coding RNA/esophageal carcinoma/esophageal squamous cell carcinoma/biomar-kers/regulation of tumors
维普
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