Objective To observe the effect of different muscle relaxation depth on optic nerve sheath diameter(ONSD)in obese patients undergoing laparoscopic sleeve gastrectomy.Methods A total of 56 obese patients undergoing elective laparoscopic sleeve gastrectomy under general anesthesia in this hospital from March to June 2023 were selected and randomly divided into the deep muscle relaxation group(group D)and moderate muscle relaxation group(group M),28 cases in each group.According to the TOF-Watch muscle re-laxation monitor,group D maintained the train of four(TOF)stimulation count as 0,moreover the post-tetan-ic count(PTC)count was 1-2,and group M maintained TOF count as 1-2.The operation time,anesthesia time and rocuronium bromide dosage were recorded.ONSD,MAP and HR at 5 min after induction intubation(T0),5 min after pneumoperitoneum establishment(T1),30 min after pneumoperitoneum establishment(T2),90 min after pneumoperitoneum establishment(T3),and 5 min after the end of pneumoperitoneum(T4)were recorded,and the occurrence of postoperative adverse reactions such as dizziness and vomiting were recorded.Results There were statistical differences in ONSD at T2 and T3 between the two groups(P＜0.05),ONSD in the group D was significantly reduced and the anesthetic time was significantly prolonged compared with the group M(P＜0.05),the dosage of rocuronium bromide in the group D was significantly increased compared with that in the group M(P＜0.05).There was no statistically significant difference in MAP and HR at T0-T4 between the two groups(P＞0.05).One case developed severe hypoxemia after sur-gery.Conclusion Compared with moderate muscle relaxation,deep muscle relaxation could alleviate the intra-operative enlargement of ONSD in obese patients undergoing laparoscopic sleeve gastrectomy.
维普
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