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具有疫苗接种和潜伏期的传染病模型的最优控制分析

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建立了具有疫苗接种和潜伏期的传染病最优控制模型,得到了基本再生数R0,构造了Lyapunov函数.当R0<1时,无病平衡点是全局渐近稳定的;当R0>1时,地方病平衡点是全局渐近稳定的.利用最优控制理论和Pontryagin原理分析了最优控制策略,使得疾病控制过程中的成本最低.用数值模拟验证了理论结果的正确性.
Analysis of optimal control for infectious disease models with vaccination and incubation periods
The optimal control of epidemic model with vaccination and latency period is established,and the basic reproduction number R0 is obtained.By constructing the Lyapunov function,it is shown that the disease-free equilibrium point is globally asymptotically stable when R0<1,and the endemic disease equilibrium point is globally asymptotically stable when R0>1.The optimal control strategy is analyzed by using the optimal control theory and Pontryagin maximum principle to minimize the total cost of disease control.Numerical simulations were experimented to verify the correction of the results approached in this paper.

basic reproduction numberLyapunov functionglobal stabilityoptimal controlPontryagin principle

豆中丽、王锐

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重庆财经学院软件学院,重庆 400055

重庆大学数学科学学院,重庆 401331

基本再生数 Lyapunov函数 全局稳定性 最优控制 Pontryagin原理

国家自然科学基金资助项目重庆市教委科技创新项目

11304403KJQN201902105

2024

东北师大学报(自然科学版)
东北师范大学

东北师大学报(自然科学版)

CSTPCD北大核心
影响因子:0.612
ISSN:1000-1832
年,卷(期):2024.56(2)
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