The best extracting technique of Semen Sojae Paratum (SSP) were optimized by orthogonal test. The extracting contents of total isoflavone and genistein in SSP were determined by UV detector and HPLC, respectively. The results showed that the best technological process of isoflavone extraction was to reflux SSP by 70％ ethanol 3 times and 2 hours for each time.The content of 70％ ethanol was 8 times of SSP.
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