Mines,improvised explosive devices and roadside bombs have become serious threat to vehicle-mounted howitzers( VMH),and the blast wave generated by mine explosion can also cause damage to the cab structure of VMH and endanger the life safety of crew. Because of the significant difference in the response of the shock wave generated by the mines explosion at different positions at the bottom of the cab,numerical simulation of the response process of the cab bottom of VMH under six explosion-shock conditions was carried out. ALE algorithm was used to establish models of soil,air and explosive,and Lagrange algorithm was used to establish the models of cab and chassis of VMH,and the fluid-solid coupling algorithm was used to calculate the propagation process of the explosion-shock wave,as well as the dynamic response of the cab of VMH in this process. The changes of shock-wave pressure,acceleration and velocity at the bottom plate of the passenger's foot position were analyzed,and the maximum shock-wave pressure,acceleration and velocity at the bottom plate of the passenger's foot position were obtained,and the damage to the cab structure under the worst-case operating conditions was analyzed. The simulation results show that the shock wave generated by the mine will make the cab floor produce greater acceleration and speed,and the cab structure will be damaged. In this case,the passengers will be injured. It is necessary to add a protective structure for the cab of VMH. The simulation results can provide reference for the design of cab protective-structure of VMH.