戊酸雌二醇联合地屈孕酮治疗宫腔粘连疗效分析
倪萍 1龙玲 1范幸1
作者信息
摘要
目的：探讨戊酸雌二醇联合地屈孕酮对宫腔粘连的治疗效果。方法回顾性分析53例宫腔粘连患者的临床资料，均于宫腔镜下宫腔粘连电切术后第2天开始服用戊酸雌二醇2 mg，3次/d，共21天，第11天开始加用地屈孕酮片10 mg，2次/d口服，连续3个周期（1个周期为21天）。结果53例患者术后3个月复查宫腔镜45例（84.90%）宫腔形态恢复良好，8例（15.10%）宫腔形态恢复欠佳，再次出现宫腔粘连；月经恢复正常者38例（71.69%），10例（18.87%）月经较术前增多，但较正常偏少，5(9.44%)例仍闭经。服用戊酸雌二醇患者4例出现乳房胀痛，无明显胃肠道反应，肝功能无明显异常。结论戊酸雌二醇联合地屈孕酮治疗宫腔粘连安全有效。
Abstract
Objecive To explore the therapeutic effects of estradiol valerate combined with dydrogesterone on intrauterine adhesions.Methods Retrospective study was employed to analyze the clinical data of 53 patients with intrauterine adhesion during 2013. After hysteroscopy electrotomy, all the patients took esradiol valerate 2mg q8h for 21 days and took dydrogesterone 10mg q12h during the last 10 days for 3 months.Results 53 patients were reexamined with hysteroscope after 3 moneths, the uterine shape recovered well in 45 patients (84.90%), the rest of patients didn’t improve and formed new intrauterine adhesion. Menstruation of 38 patients (71.69%) resumed normal, 10 patients (18.87%) fewer than normer, 5 patients (9.44%) still amenorrhoea. No gastrointestinal reactions occurred and liver function examination was normal for all the patients but 4 has beast pain.Conclusion Estradiol valerate combined with dydrogesterone is an effective and save therapy method on intrauterine adhesions.
关键词
宫腔粘连/宫腔镜/戊酸雌二醇/地屈孕酮Key words
Intrauterine adhesions/Hysteroscopy/Estradiol valerate/Dydrogesterone引用本文复制引用
出版年
2016
NETL
NSTL
维普
万方数据