Medication rule of Jiang Baihua in treatment of pulmonary nodules:A study based on data mining
Objective:To investigate the medication rule of Chief Physician Jiang Baihua in the treatment of pulmonary nodules based on data mining.Methods:Case data were collected from the patients with pulmonary nodules who attended the outpatient service of Chief Physician Jiang Baihua for the first time from December 1,2021 to October 31,2022.Excel 2021 was used to analyze the frequency of traditional Chinese medicine(TCM)drugs;SPSS Modeler 18.0 was used to perform the association rule analysis of drugs;Cytoscape 3.9.1 was used for network visualization;SPSS 26.0 was used for the hierarchical cluster analysis of drugs.Results:A total of 384 prescriptions were included,involving 165 TCM drugs,with a total frequency of 13803 times.There were 45 drugs with a frequency of＞120 times,with the top 5 drugs of tangerine peel,Codonopsis pilosula,Atractylodes macroceph-ala Koidz.fried with bran,Astragalus membranaceus,and Salvia miltiorrhiza.The top 4 functions were tonifying de-ficiency,activating blood and resolving stasis,clearing heat,and resolving phlegm and relieving cough and asthma.Most drugs were cold,warm or neutral in nature and had a bitter,sweet or pungent taste,and they mainly entered the lung,liver,spleen,and stomach meridians.Conclusion:Chief Physician Jiang Baihua thinks that vital Qi defi-ciency and internal accumulation of phlegm stasis are the main pathogenesis of pulmonary nodules,and the core pre-scriptions for treatment should include deficiency-tonifying herbs,blood-activating and stasis-resolving drugs,and phlegm-eliminating,cough-relieving,and asthma-relieving drugs.
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万方数据
