Clinical effect of Yan's Mapu granules of Shanghai-style Traditional Chinese Medicine in treatment of acute cerebral infarction with upper hyperactivity of liver Yang:An analysis of 60 cases
Objective:To investigate the clinical effect of Yan's Mapu granules of Shanghai-style Tradition-al Chinese Medicine in the treatment of acute cerebral infarction with upper hyperactivity of liver Yang.Methods:A total of 120 patients with acute cerebral infarction with upper hyperactivity of liver Yang were selected and randomly divided into treatment group and control group,with 60 patients in each group.In addition to the basic Western standard treatment of cerebral infarction,the patients in the treatment group were given Yan's Mapu granules,and those in the control group were given Tianma Gouteng decoction;the course of treatment was 30 days for both groups.The two groups were observed in terms of TCM syndrome score,National Institutes of Health Stroke Scale(NIHSS)score,blood pressure,inflammation indicators,largest plaque area on color Doppler ultrasound for cervical vessels,blood lipid levels,and treatment outcome of TCM syndrome.Results:There was a significant difference in the overall response rate of TCM syndrome between the treatment group and the control group[98.3％(59/60)vs 85.0％(51/60),P＜0.01].Compared with the control group,the treatment group had significantly greater reduc-tions in TCM syndrome score,NIHSS score,and blood pressure parameters and significantly better improvements in the inflammation indicators high-sensitivity C-reactive protein and interleukin-6,blood lipid levels,and largest plaque area on color Doppler ultrasound for cervical vessels(P＜0.05).Conclusion:Yan's Mapu granules of Shanghai-style Traditional Chinese Medicine has a marked clinical effect in the treatment of acute cerebral infarc-tion with upper hyperactivity of liver Yang and thus provides a reference for clinical practice.
ischemic strokeupper hyperactivity of liver YangYan's Mapu granulesShanghai-style Tra-ditional Chinese Medicine
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