Clinical effect of Yinhuang Qingfei capsules in treatment of asymptomatic and mild/common severe acute respiratory syndrome coronavirus 2 infection:An analysis of 242 cases
Objective:To investigate the clinical effect of Yinhuang Qingfei capsules in the treatment of asymp-tomatic and mild/common severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Methods:A total of 362 patients with SARS-CoV-2 infection were divided into treatment group with 242 patients and control group with 120 patients according to their treatment regimen.The patients in the control group were given standard treatment regi-men,and those in the treatment group were given Yinhuang Qingfei capsules in addition to the treatment in the control group.The two groups were observed in terms of mean hospital stay,mean time to nucleic acid clearance,TCM syn-drome score,and progression to severe/critical illness,and clinical outcome was compared between the two groups.Results:There was a significant difference in overall response rate between the treatment group and the control group[97.52％(236/242)vs 95.00％(114/120),P＜0.05).Compared with the control group,the treatment group had significantly shorter mean hospital stay and mean time to nucleic acid clearance(P＜0.05).After 7 days of treat-ment,both groups had a significant change in TCM syndrome score,and there was a significant difference in TCM syn-drome score between the two groups(P＜0.05);after 15 days of treatment,both groups had a TCM syndrome score of 0.Progression to severe/critical illness was not observed in either group.Conclusion:Compared with the standard treat-ment regimen alone,standard treatment regimen combined with Yinhuang Qingfei capsules can effectively shorten the length of hospital stay and the time to nucleic acid clearance and improve TCM symptoms in patients with asymptomatic and mild/common SARS-CoV-2 infection.
severe acute respiratory syndrome coronavirus 2 infectionasymptomaticmild/commonYinhuang Qingfei capsules
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