Medication rule of Zhang Qiwen in treatment of epilepsy:A study based on data mining
Objective:To investigate the medication rule of National Famous TCM Doctor Zhang Qiwen in the treatment of epilepsy based on data mining.Methods:Medical records of epilepsy treated by Zhang Qiwen from September 1st,1998 to September 30th,2019 were collected,and standardized processing was performed for the data in the medical records to construct a database.Cloud Platform of Ancient and Modem Medical Records V2.3.5 was used to analyze frequency of use,four properties and five tastes,function,and meridian entry and perform associa-tion rule analysis and cluster analysis,and clinical experience was summarized.Results:A total of 40 prescriptions were obtained,involving 120 TCM drugs.The top 10 TCM drugs were scorpion,centipede,Bombyx batryticatus,Ra-dix Glycyrrhizae Preparata,malt,hawthorn fruit,Uncaria,Comu Saigae Tataricae,pearl,and bezoar.Most drugs were neutral or warm in nature and mainly had a sweet,pungent or bitter taste,and they mainly entered the liver,lung,and spleen meridians.The main functions included dredging collaterals and relieving pain,counteracting toxic sub-stances and resolving static blood,and extinguishing wind and relieving spasm.The drug combinations with the high degree of support were scorpion-centipede,scorpion-Bombyx batryticatus,Bombyx batryticatus-centipede,Uncaria-scorpion,and Uncaria-centipede.Conclusion:Zhang Qiwen addresses both the symptoms and root causes in the treatment of epilepsy,with a focus on extinguishing wind in symptomatic treatment and strengthening the spleen in radical treatment.