Clinical effect of modified Guishao Shenqi Dihuang decoction in treatment of chronic renal insufficiency:An analysis of 50 cases
Objective:To investigate the clinical effect of modified Guishao Shenqi Dihuang decoction in the treatment of chronic renal insufficiency with deficiency of liver and kidney and intermingled stasis and toxin.Methods:A total of 100 patients with chronic renal insufficiency with deficiency of liver and kidney and inter-mingled stasis and toxin were divided into treatment group and control group using a random number table,with 50 patients in each group.The patients in the control group received conventional Western medicine treatment,and those in the treatment group received modified Guishao Shenqi Dihuang decoction in addition to the treatment in the control group.Each course of treatment was 1 month,and both groups were treated for three courses.The two groups were compared in terms of overall response,traditional Chinese medicine(TCM)syndrome score,renal function pa-rameters(serum creatinine,creatinine clearance rate,blood urea nitrogen,cystatin C,and 24-hour urinary pro-tein),and quality of life score.Results:There was a significant difference in overall response rate between the treat-ment group and the control group[78.00％(39/50)vs 46.00％(23/50),P＜0.01].After treatment,both groups had significant changes in TCM syndrome score,renal function parameters,and quality of life score,and there were significant differences in these indicators between the two groups after treatment(P＜0.05).Conclusion:Modified Guishao Shenqi Dihuang decoction can improve the treatment outcome and quality of life of patients with chronic re-nal insufficiency with deficiency of liver and kidney and intermingled stasis and toxin.
chronic renal insufficiencydeficiency of liver and kidney and intermingled stasis and toxinmodified Guishao Shenqi Dihuang decoction
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