Medication rule of Liu Min in treatment of breast cancer:An analysis based on Traditional Chinese Medicine Inheritance Support System
Objective:To investigate the medication rule of Professor Liu Min in the treatment of breast cancer based on Traditional Chinese Medicine Inheritance Support System(V3.0).Methods:Prescriptions of the first consultation were collected from 276 patients with breast cancer who attended the outpatient service of Profes-sor Liu from January 2021 to June 2023,and Traditional Chinese Medicine Inheritance Support System(V3.0)was used for standardized data entry to establish a database of prescriptions.The modules of this system,including prescription analysis,were used for data mining,and the medication rule of the prescriptions was analyzed.Results:Among the 27 6 prescriptions,the top 5 drugs were Comus officinalis,fried Atractylodes macro-cephala Koidz.,fried Radix Paeoniae Alba,Herba Epimedii,and Codonopsis pilosula.As for the nature of the drug,warm drugs had the highest frequency,followed by neutral,cold,cool,and hot drugs;as for the taste of the drug,the drugs with a sweet taste had the highest frequency,followed by those with a pungent,bitter,sour or salty taste;as for meridian entry,the drugs entering the liver meridian had the highest frequency of 2004 times,followed by those entering the spleen or kidney meridians.Commonly used drug combinations included Comus officinalis-fried Atractylodes macrocephala Koidz.,Comus officinalis-fried Radix Paeoniae Alba,fried Atractylodes macro-cephala Koidz.-fried Radix Paeoniae Alba,Comus officinalis-Herba Epimedii,and Comus officinalis-fried At-ractylodes macrocephala Koidz.-fried Radix Paeoniae Alba.The association rule analysis obtained 7 association rules,and the cluster analysis obtained 6 clusters of prescriptions.Conclusion:In the treatment of breast cancer,Professor Liu mainly applies the principles of tonifying the kidney,invigorating the spleen,and soothing the liver,in combination with stasis-resolving,detoxicating,and antitumor drugs,which reflects the medication rule of strengthening vital Qi and eliminating pathogens.
breast cancerLiu MinTraditional Chinese Medicine Inheritance Support Systemprescription ruledata mining
NETL
NSTL
万方数据
