Medication rule of Sun Dawu in treatment of lumbago:A study based on data mining
Objective:To investigate the medication rule of Professor Sun Dawu in the treatment of lumbago based on data mining.Methods:Medical records were collected from the patients with lumbago who were treated by Professor Sun,and Traditional Chinese Medicine Inheritance Support System(V2.5)was used to perform data min-ing,including the frequency of use of traditional Chinese medicine(TCM)drugs,nature/taste/meridian entry,and cluster analysis,to analyze related medication rules and obtain core drug combinations and new prescriptions.Results:A total of 158 cases were included,involving 158 prescriptions and 61 TCM drugs.The top 10 drugs in terms of frequency of use were Eucommia ulmoides,Radix Glycyrrhizae,Rhizoma Cibotii,teasel root,Rhizo-ma Corydalis,Radix Achyranthis Bidentatae,Rhizoma Drynariae,Angelica pubescens,Herba Speranskiae Tubercu-latae,and Spatholobi Caulis.The main functions of the TCM drugs included strengthening tendons and bones,activa-ting blood,and relieving pain.Most drugs were warm,neutral or cold in nature and had a bitter,sweet or pungent taste,and they mainly entered the liver,kidney,and spleen meridians.The association rule analysis and the cluster analysis obtained 12 high-frequency drug combinations and 3 new prescriptions.Conclusion:In the treatment of lumbago,Professor Sun emphasizes the treatment in accordance with the patient's individuality,seasonal condi-tions,and local conditions,applies kidney-tonifying and blood-activating therapy as the main idea,and focuses on the care of the spleen and the stomach,with the treatment principles of tonifying liver and kidney,strengthening ten-dons and bones,activating blood and resolving stasis,and dispelling pathogenic wind and removing dampness.
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