Clinical effect of Tangshenkang granules in treatment of diabetic kidney disease with deficiency of both Qi and Yin and blood stasis syndrome:An analysis of 30 cases
Objective:To investigate the clinical effect of Tangshenkang granules in the treatment of diabetic kidney with stage Ⅲ disease(DKD)with deficiency of both Qi and Yin and blood stasis syndrome.Methods:A total of 60 patients with stage Ⅲ DKD with deficiency of both Qi and Yin and blood stasis syndrome were collected and randomly divided into treatment group and control group,with 30 patients in each group.The patients in the control group received conventional Western medicine treatment,and those in the treatment group received Tangshenkang granules in addition to the treatment in the control group;the course of treatment was 8 weeks for both groups.The two groups were compared in terms of traditional Chinese medicine(TCM)syndrome score,fasting plasma glucose,2-hour postprandial blood glucose,urinary microalbumin/creatinine ratio(ACR),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),cystatin C(Cys-C),and adverse reactions.Results:The treat-ment group had a significantly higher overall response rate than the control group[86.67％(26/30)vs 53.33％(16/30),P＜0.05].Compared with the control group,the treatment group had a significantly lower levels of ACR,hs-CRP,IL-6,and Cys-C(P＜0.05).The adverse reaction rates in both qroups were 9.99％(16/30).Conclusion:Tangshenkang granules have a marked clinical effect in the treatment of DKD with deficiency of both Qi and Yin and blood stasis syndrome and can effectively alleviate proteinuria,improve renal function,and reduce the levels of inflammatory factors.
diabetic kidney diseasestage Ⅲdeficiency of both Qi and Yin and blood stasis syndromeTangshen-kang granules
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