Medication rule of National Chinese Medicine Master Liu Shangyi in treatment of Yin deficiency syndrome:A study based on data mining
Objective:To investigate the medication rule of National Chinese Medicine Master Professor Liu Shangyi in the treatment of Yin deficiency syndrome.Methods:Medical records were collected from the pa-tients with Yin deficiency syndrome who were treated at the outpatient service of Professor Liu from January 1,2018 to January 1,2023,and Cloud Platform of Ancient and Modern Medical Records V2.1 was used to analyze traditional Chinese medicine(TCM)diagnosis,Western medicine diagnosis,TCM syndrome types,principles and methods of treatment,and frequency of medication.Results:A total of 6300 medical records were included.Yin deficiency syndrome was more common in the three age groups of 50-59 years,40-49 years,and 60-69 years.The top three TCM diagnoses based on TCM syndrome were lung accumulation,colorectal cancer,and breast cancer,and the top three Western medicine diagnoses were lung cancer,intestinal cancer,and breast cancer.The top three TCM syndrome types were liver-kidney Yin deficiency,Yin deficiency and heat-toxicity syndrome,and Yin deficiency and dryness-heat syndrome.The top three principles and methods of treatment were tonifying the liver and the kidney,tonifying the kidney and nourishing Yin,and nourishing Yin,clearing heat,and detoxicating.The top ten TCM drugs in terms of frequency of use were vinegar-processed Curcuma zedoaria,vine-gar-processed turtle shell,Rabdosia rubescens,Comus officinalis,Humulus scandens,wine-processed Polygona-tum sibiricum,Ranunculus ternatus Thunb.,lily,fried Semen Sinapis,and vinegar-processed tortoise shell(with a frequency of＞480 times).The association analysis of TCM drug combinations obtained 20 drug combinations with a co-occurrence frequency of＞1880 times,as well as 8 core combinations with 3 drugs and 4 new prescrip-tions.Conclusion:Data mining analysis obtains the core drugs,principles and methods of treatment,and clinical practice thinking of Professor Liu in the treatment of Yin deficiency syndrome and summarizes the core treatment principle of tonifying the liver and the kidney.
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万方数据
