Medication rule of He Yongheng in treatment of functional constipation:A study based on data mining
Objective:To investigate the medication rule of Professor He Yongheng in the treatment of functional constipation(FC)based on data mining.Methods:Medical records were collected from the patients with FC who were di-agnosed and treated at the outpatient service of Professor He from September 1,2022 to September 30,2023,and Tradition-al Chinese Medicine Inheritance Support System V3.0 was used for syndrome differentiation and typing.The drugs used were analyzed in terms of frequency,nature,taste,and meridian entry,and association rule analysis and cluster analysis were also performed.Results:A total of 174 medical records were included,involving 174 patients in total.For syndrome differentiation and typing,Qi stagnation constipation,heat stagnation constipation,and Yin deficiency constipation.A total of 82 traditional Chinese medicine drugs were involved,and the top three drugs in terms of frequency of use were Atrac-tylodes macrocephala Koidz.,Fructus Cannabis,and Fructus Aurantii.Most drugs had a warm,cold,or neutral nature and a bitter,sweet,or pungent taste,and they mainly entered the spleen,stomach,and large intestine meridians.The top five functions were tonifying deficiency,regulating Qi,clearing heat,purgating,and promoting diuresis and draining damp-ness.The association rule analysis obtained the prescriptions with the core drugs of Atractylodes macrocephala Koidz.,Radix Paeoniae Alba,Fructus Cannabis,Semen Armeniacae Amarum,Fructus Aurantii,Magnolia officinalis,and cassia seed.The cluster analysis obtained 5 core drug combinations.Conclusion:In the treatment of FC,Professor He emphasizes the core treatment principle of moving Qi and guiding stagnation and clearing heat and promoting diuresis and determines the score prescriptions of Atractylodes macrocephala Koidz.,Radix Paeoniae Alba,Fructus Cannabis,Semen Armeniacae Amarum,Fructus Aurantii,Magnolia officinalis,and cassia seed,which can provide a reference for the clinical treatment of FC.
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万方数据
