摘要
目的:基于数据挖掘探析王庆来教授治疗膝痹的用药规律.方法:收集整理2021年1月1日至2024年1月28日王教授运用中药治疗膝痹的医案.运用IBM SPSS Modeler 18.0软件进行关联规则分析,采用SPSS statistics 26.0软件进行药物频数统计和聚类分析.结果:共纳入有效处方403首,中药139味,总频次为5 494次,使用频次排前5位的中药分别是川芎、牛膝、薏苡仁、陈皮、忍冬藤.药性以温、平为主,药味以甘、苦为主,多归肝、脾、肺经.药物关联分析结果显示常用药物组合为伸筋草-路路通、忍冬藤-丝瓜络、川芎-丝瓜络等.聚类分析得到5个聚类组合.常用的方剂为滑膜炎方、补气运脾方.结论:王教授治疗膝痹以清热祛湿、补气运脾为法,辨病与辨证相结合,注重标本同治.
Abstract
Objective:To investigate the medication rule of Professor Wang Qinglai in the treatment of knee arthralgia based on data mining.Methods:Medical records were collected from the patients with knee arthral-gia who received traditional Chinese medicine(TCM)treatment by Professor Wang from January 1,2021 to Janu-ary 28,2024.IBM SPSS Modeler 18.0 was used for association rule analysis,and SPSS statistics 26.0 was used for drug frequency statistics and cluster analysis.Results:A total of 403 valid prescriptions were included,invol-ving 139 TCM drugs,with a total frequency of 5 494 times,and the top 5 TCM drugs in terms of frequency were Rhizoma Chuanxiong,Radix Achyranthis Bidentatae,coix seed,tangerine peel,and Caulis Lonicerae.Most drugs were warm or neutral in nature and had a sweet or bitter taste,and they mainly entered the liver,spleen,and lung meridians.The drug association analysis showed that the commonly used drug combinations included Lycopodium clavatum-Liquidambaris Fructus,Caulis Lonicerae-loofah sponge,Rhizoma Chuanxiong-loofash sponge.The cluster analysis obtained five clusters.The commonly used prescriptions included synovitis prescription and qi-tonifying and spleen-activating prescription.Conclusion:Professor Wang uses the heat-clearing and dampness-eliminating method and the Qi-tonifying and spleen-activating method in the treatment of knee arthralgia,with a combination of disease differentiation and syndrome differentiation and a focus on simultaneous treatment of both manifestations and root causes.
基金项目
浙江省王庆来名老中医专家传承工作室建设项目(GZS2021034)
维普
万方数据