Medication rule of Wang Qinglai in treatment of knee arthralgia:A study based on data mining
Objective:To investigate the medication rule of Professor Wang Qinglai in the treatment of knee arthralgia based on data mining.Methods:Medical records were collected from the patients with knee arthral-gia who received traditional Chinese medicine(TCM)treatment by Professor Wang from January 1,2021 to Janu-ary 28,2024.IBM SPSS Modeler 18.0 was used for association rule analysis,and SPSS statistics 26.0 was used for drug frequency statistics and cluster analysis.Results:A total of 403 valid prescriptions were included,invol-ving 139 TCM drugs,with a total frequency of 5 494 times,and the top 5 TCM drugs in terms of frequency were Rhizoma Chuanxiong,Radix Achyranthis Bidentatae,coix seed,tangerine peel,and Caulis Lonicerae.Most drugs were warm or neutral in nature and had a sweet or bitter taste,and they mainly entered the liver,spleen,and lung meridians.The drug association analysis showed that the commonly used drug combinations included Lycopodium clavatum-Liquidambaris Fructus,Caulis Lonicerae-loofah sponge,Rhizoma Chuanxiong-loofash sponge.The cluster analysis obtained five clusters.The commonly used prescriptions included synovitis prescription and qi-tonifying and spleen-activating prescription.Conclusion:Professor Wang uses the heat-clearing and dampness-eliminating method and the Qi-tonifying and spleen-activating method in the treatment of knee arthralgia,with a combination of disease differentiation and syndrome differentiation and a focus on simultaneous treatment of both manifestations and root causes.