Medical records of emotional disease with gastrointestinal symptoms from the Ming and Qing Dynasties
To investigate the disease names,disease nature,disease location,and medication rule of e-motional disease with gastrointestinal symptoms in the Ming and Qing Dynasties.Methods:Chinese Medical Clas-sics was used to obtain the medical records of emotional disease with gastrointestinal symptoms from the Ming and Qing Dynasties,and a database was established.Excel software was used to perform descriptive statistics of dis-ease names,disease nature,disease location,and medication frequency,and RStudio software was used to per-form the association rule analysis of drugs.Results:A total of 119 medical records were included,involving 29 disease names.As for the tendency of cold and heat,absence of cold and heat accounted for the highest propor-tion of 62.18％,followed by heat syndrome accounting for 36.97％,with only 1 case of cold syndrome.As for the disease nature of deficiency and excess,excess syndrome accounted for 51.26％,and the syndrome of inter-mingled deficiency and excess accounted for 42.02％.A total of 10 disease locations were involved,among which the top 4 disease locations in terms of frequency were the stomach(119 times),the liver(97 times),the spleen(96 times),and the lungs(16 times).There were 9 drugs with a frequency of use of＞20％,i.e.,Po-ria cocos,Pinellia ternata,Radix Paeoniae Alba,tangerine peel,Curcuma aromatica,Coptis chinensis,Angeli-ca sinensis,Panax ginseng,and Rhizoma Cyperi.The association rule analysis obtained 4 drug combinations for the treatment of emotional disease with gastrointestinal symptoms,i.e.,Fructus Aurantii Immaturus-Pinellia ter-nata,Panax ginseng-Poria cocos,Pinellia ternata-Poria cocos,and Pinellia ternata-tangerine peel-Poria co-cos.Conclusion:Emotional disease is closely associated with gastrointestinal symptoms,and the spleen and the stomach play a special role in various syndromes of emotional disease,suggesting that physicians should pay at-tention to the regulation and protection of the spleen and the stomach during the treatment of emotional disease.Compared with gastrointestinal diseases due to other causes,dysfunction of the liver and the lungs is a prominent factor among the pathogenesis factors of emotion-related gastrointestinal diseases,which provides a theoretical ba-sis for the treatment of this disease from the liver and the lungs.Based on the tendency of deficiency/excess and cold/heat of this disease,drugs that promote heat and induce fire should be used with caution in clinical prac-tice,and tonifying deficiency should be combined with excess purgation for treatment.
emotional diseasegastrointestinal symptomsMing and Qing Dynastiesmedical recordsda-ta mining
万方数据
维普
