Medication rule of Zhang Xiaoping in treatment of chronic non-atrophic gastritis:A study based on data mining
Objective:To investigate the medication rule of Professor Zhang Xiaoping in the treatment of chronic non-atrophic gastritis(CNAG)based on data mining.Methods:Initial diagnosis data were collected from the patients with CNAG who were diagnosed and treated in the consulting room of Professor Zhang in The Affiliated Hospital of Jiangxi Uni-versity of Traditional Chinese Medicine from December 3,2019 to June 28,2022.Excel was used to analyze the frequency,nature,taste,meridian entry,and category of traditional Chinese medicine(TCM)drugs,and SPSS Statistics 26.0,SPSS Modeler 18.0,and Cytoscape 3.7.2 were used to perform association rule analysis and cluster analysis.Results:A total of 327 prescriptions were included,involving 128 TCM drugs.The accumulative frequency of use of TCM drugs reached 5 048,and there were 25 TCM drugs with a frequency of ≥ 50,with the top five drugs of Radix Glycyrrhizae Preparata,roasted malt,fried grain sprouts,Coptis chinensis,and Rhizoma Bletillae.Most drugs had a cold,warm or neutral nature and a bitter,sweet or pungent taste,and they mainly entered the spleen,stomach,and liver meridians.In terms of category,deficiency-tonifying,Qi-regulating,digestion-promoting,and heat-clearing drugs were mainly used.The most commonly used drug combination was roasted malt-fried grain sprouts.The cluster analysis obtained three TCM drug combinations.Conclusion:Professor Zhang believes deficiency of spleen and stomach and qi-movement stagnation are the main patho-geneses of CNAG and applies the treatment methods of strengthening the spleen,tonifying the stomach,and regulating Qi-movement,with an emphasis on the rise-fall and entry-exit of Qi-movement and the balance between dampness and dr-ying and between intake and digestion.
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