Medication rule of Pan Liqun in syndrome differentiation-based treatment of gastric cancer:A study based on data mining
Objective:To investigate the medication rule of Professor Pan Liqun in the treatment of gastric cancer using Traditional Chinese Medicine Inheritance Support System(V3.0).Methods:Medical records were col-lected from the patients with gastric cancer who were treated at the outpatient service of Professor Pan from January 1 to December 31,2022.The methods such as association rule analysis and entropy clustering in Traditional Chinese Medicine Inheritance Support System(V3.0)were used to perform a statistical analysis of the medications and pre-scriptions in the database and identify core prescriptions and drug combinations.Results:A total of 163 prescrip-tions were included,involving 216 traditional Chinese medicine(TCM)drugs,and the top 10 TCM drugs in terms of frequency of use were Radix Glycyrrhizae,Poria cocos,Atractylodes macrocephala Koidz.,tangerine peel,Radix Paeoniae Alba,Dendrobium,Fructus Aurantii,Ramulus Cinnamomi,Radix Adenophorae,and Magnolia officinalis.Most drugs had a warm or neutral nature and a sweet,bitter or pungent taste,and they mainly entered the spleen,stomach,and lung meridians,with the main functions of tonifying deficiency,regulating Qi,promoting diuresis and draining dampness,and resolving phlegm and relieving cough and asthma.A total of 10 core drug combinations were obtained,and the hierarchical cluster analysis obtained 3 new prescriptions.Conclusion:Professor Pan consist-ently uses the method of"activating the spleen and harmonizing the stomach"in the diagnosis and treatment of gas-tric cancer and masters the pathogenic features of overall deficiency and local excess,with the main principle of strengthening vital Qi and eliminating pathogen.
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