Medication rule of the treatment of rheumatism in Prolonging Life and Preserving the Origin:A study based on data mining
Objective:To investigate the syndrome differentiation-based treatment and prescriptions for rheumatism in Prolonging Life and Preserving the Origin and the prescription and medication rules of Gong Tingxian in the treatment of rheumatism.Methods:A database was established for the prescriptions for rheumatism in Prolon-ging Life and Preserving the Origin:Volume V.IBM SPSS Modeler 18.0 software was used to perform the associa-tion rule analysis,and SPSS statistics 26.0 software was used to analyze the drugs in terms of frequency of use,na-ture/taste/meridian entry,function,and association rule.Results:A total of 51 prescriptions were included,invol-ving 120 traditional Chinese medicine(TCM)drugs,with a total frequency of use of 586 times.The top 10 TCM drugs in terms of frequency of use were Angelica sinensis,Radix Glycyrrhizae Preparata,Rhizoma Chuanxiong,No-topterygium incisum,ginger,tangerine peel,Divaricate Saposhnikovia Root,Poria cocos,Panax ginseng,and Astraga-lus membranaceus.Most drugs were warm,neutral or cold in nature and had a pungent,sweet or bitter taste,and they mainly entered the spleen,liver,and lung meridians.The drugs were mainly deficiency-tonifying drugs,and the hierarchical cluster analysis of high-frequency drugs obtained 25 drug pairs and 4 drug combinations.Conclusion:In the treatment of rheumatism,Gong Tingxian emphasized the comprehensive analysis of both pulse manifestation and symptoms,stressed the treatment from the spleen and the liver,and mainly adopted the methods of strengthening vital Qi and tonifying deficiency,drying dampness and resolving phlegm,clearing heat and dredging collaterals,acti-vating blood and resolving stasis,and opening the interstices and expelling pathogens.
rheumatismProlonging Life and Preserving the Origindata miningmedication rule