Influence of construction of demonstration area for viral hepatitis B prevention and treatment on epidemiological characteristics in Wuwei city
Objective To analyze the epidemiological characteristics of viral hepatitis B(hepatitis B for short)during the 14 years(2009-2022)construction of demonstration area for hepatitis B prevention and control inn Wuwei city,and provide scientific basis for further formulating hepatitis B prevention and control strategies.Methods The reported data of hepatitis B and seroepidemiological survey in Wuwei city from 2009 to 2022 were collected from disease monitoring report management information system,and analyzed with the descriptive epidemiology method.Results The incidence rate of hepatitis B decreased from 637.70/100 000 in 2009 to 66.58/100 000 in 2022,and showed decreasing trend(Z=-66.897,P<0.001).The incidence rate of hepatitis B decreased by 91.66%in the enhanced intervention demonstration area(Liangzhou district),with average annual decrease of 17.39%.The cases aged 20-29 year old were the main,accounting for 24.48%.The incidence rate of hepatitis B in2022 decreased by 41.02%compared with 2009.The positive rate of hepatitis B surface antigen decreased from 7.31%in 2010 to 4.08%in 2020 in the population.Conclusions After 14 years of the construction of demonstration area,the incidence rate of hepatitis B and positive rate of surface antigen significantly decrease.The proportion of hepatitis B cases significantly decreases in the viral hepatitis cases.The"Wuwei model"that is suitable for hepatitis B prevention and treatment in the western depressed area of China is formed.