首页|河南省确山县疑似布鲁氏菌病患者血清抗体检测结果分析

河南省确山县疑似布鲁氏菌病患者血清抗体检测结果分析

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目的 了解2019-2022年河南省确山县布鲁氏菌病的流行特征,为制订布鲁氏菌病防控策略和措施提供科学依据.方法 按WS269-2019《布鲁氏菌病诊断》,采用虎红平板凝集试验(RBT)和试管凝集试验(SAT)检测确山县疾病预防控制中心门诊部疑似布鲁氏菌病患者血清抗体,滴度为1∶100++及以上为阳性.采用EXCEL 2013 录入数据,运用SPSS 17.0统计分析,以卡方检验比较率的差异,P<0.05 为差异有统计学意义.结果 2019-2022年共检查患者3 608例,阳性443例、阳性率12.28%,阳性率2022年最高(14.14%)、2019年最低(10.53%),不同年度阳性率差异无统计学意义(x2=7.199,P>0.05);阳性滴度效价以1∶400++~组为主(66.37%);男女性别比2.49∶1,阳性率男性12.04%、女性12.92%,差异无统计学意义(x2=0.516,P>0.05);30~60岁组阳性人数占总阳性数的87.36%.阳性率30岁~组最高(15.09%),不同年龄组差异有统计学意义(x2=20.061,P<0.05).职业以农民为主、占全部病例的97.97%.结论 确山县布鲁氏菌病疫情形势严峻,男性青壮年农民养殖从业人员为高危人群,应加强源头防治,发展科学、规范化养殖,做好高危人群健康教育和定期监测,降低布鲁氏菌病危害、做好疫情控制.
Analysis of detection results of serum antibody from suspected brucellosis patients in Queshan county,Henan province
Objective To investigate the epidemic characteristics of brucellosis in Queshan county,Henan province from 2019 to 2022,and provide scientific basis for formulating the strategies and measures of brucellosis prevention and control.Methods The serum antibody of suspected brucellosis patients in the outpatient department of the center for disease control and prevention(CDC)of Queshan county were detected by the rose bengal plate test(RBPT)and standard tube agglutination test(SAT),according to WS 269-2019 Brucellosis Diagnosis.The titer of 1∶100++and above was positive.The data was input in EXCEL 2013 for analysis with SPSS 17.0.The difference of rates was compared with Chi-square test,and the difference was statistical if P<0.05.Results From 2019 to 2022,a total of 3 608 patients were examined,and 443 cases were positive,with the positive rate of 12.28%.The positive rate was the highest in 2022(14.14%)and the lowest in 2019(10.53%).There was no statistical difference in the positive rates of different years(x2=7.199,P>0.05).The positive titer of 1∶400++~was mainly(66.37%).The ratio of the male to the female was 2.49∶1.The positive rate was 12.04%in the male,and 12.92%in the female,without statistical difference(x2=0.516,P>0.05).The number of positive patients aged from 30 to 60 years accounted for 87.36%of the total positive patients.The positive rate was the highest in the age group of 30-years(15.09%),and the difference was statistically significant in the positive rates of different age groups(x2=20.061,P<0.05).Most cases were farmers,and accounted for 97.97%of all cases.Conclusions The epidemic situation of brucellosis is serious in Queshan county.The male young farmers working for livestock husbandry are population with high-risk.It is necessary to strengthen the source prevention and control,develop scientific and standardized breeding methods,and do well in health education and regular monitoring in the population with high-risk for reducing the harm of brucellosis and controlling the epidemic.

BrucellosisSerum antibodyAgglutination testPositive rateTiter

王永生

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河南省确山县疾病预防控制中心,河南确山 463200

布鲁氏菌病 血清抗体 凝集试验 阳性率 滴度效价

2024

疾病预防控制通报
新疆疾病预防控制中心

疾病预防控制通报

ISSN:1000-3711
年,卷(期):2024.39(1)