Analysis of newly reported HIV/AIDS in a city of Xinjiang from 2018 to 2022
Objective To analyze the basic situation,(western blot)WB banding pattern and CD4+T cell count of newly reported HIV infected patients in a city of Xinjiang from 2018 to 2022,and explore the correlation between the characteristics of recent infection banding pattern and the immune status.Methods The data of newly reported HIV/AIDS cases from 2018 to 2022 and the results of CD4+T cell count,WB test and new infection test(LAg-Avidity EIA)were collected and analyzed with Chi-square and Logistic regression methods.Results There were all 688 newly reported HIV/AIDS patients.The male,farmer,junior high school education and sexual transmission were the main,with 133 newly infected cases,accounting for 19.33％.Univariate analysis showed that the positive rates of gp41(Wald x2=16.101)and p31(Wald x2=8.005)in the newly infected samples was lower than that in previous infected samples(P＜0.05).Multiple Logistic regression analysis showed that the deletion of gp41 band was 3.847 times more likely to be identified as a new infection than the appearance of gp41 band(OR=3.847,95％CI:1.780-8.314).There were statistical differences in the detection rates of p51 and p17 in different immunosuppressive groups(P＜0.05).Conclusions There is correlation between the WB banding pattern and the immune status of the patients.The deletion of gp41 band may be one sign of WB band pattern of newly infected patients.
HIV-1WB band patternRecent infectionLAg-Avidity EIA
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NSTL
万方数据
